Dr. Alessio Fasano, MD presented "How Nutrition Can Impact Microbiome Composition-Permeability-Immune Response Triangulation in The Gastrointestinal Tract Dictating the Balance Between Health And Disease" at the SCDROCKS Conference 2023 hosted by the Specific Carbohydrate Diet Association at Bellevue College.   

Video Objectives: 

• Lesson Learned from a Smart Pathogen 
• Vaccine Trial Outcome *Proposed Zot Mechanism of Action 
• The Zonulin Pathway 
• Literature Report on Zonulin and Chronic Inflammatory Diseases 
• Feeding Disorders: A close Interaction Between Psyche and Nutrition with an Inflammatory Component 
• The Epidemics of Chronic Inflammatory Diseases (CID) in the Western Hemisphere: The Hygiene Hypothesis 
• How Zonulin-Mediated Increased Ag Trafficking Leads to Chronic Inflammation 
• The Changing Face of Gut Microbes 
• The Microbiome is Essential to Health 
• Why the first 1000 days of Life are Instrumental for Clinical Diversity 
• Role of Breastmilk 
• Cycle of Microbiota Transmission 
• Baby's first bacteria 
• The wisdom of microscopic species 
• Role of Gut Microbiome in Chronic Inflammatory Diseases 
• Autoimmunity: The Celiac Disease Paradigm 
• CD Pathogenesis: More than Genes + Environment Paradigm 
• Celiac Disease Genome, Environment, Microbiome, and Metabolomic Studies 
• Obesity 
• Risk Factors for Pediatric Obesity 
• Aging *Manipulating the Microbiome to maintain health  

Dr. Fasano holds the following titles:  

• Chief of the Division of Pediatric Gastroenterology and Nutrition, Mass General for Children  
• Vice Chair of Research – Mass General for Children 
• Director of The Mucosal Immunology and Biology Research Center and The Center for Celiac Research and Treatment                              
• Professor of Pediatrics, Harvard Medical School  
• Professor of Nutrition, Harvard T.H. Chan School of Public Health  

A pediatric gastroenterologist, Alessio Fasano, MD is head of the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital (MGH) and professor of nutrition at the Harvard T.H. Chan School of Public Health. In 2000, his group discovered zonulin, a protein associated with gut dysbiosis that regulates intestinal tight junctions. His basic research focuses on bacterial pathogenesis, gut microbiome composition and function in health and disease, the regulation of gut permeability, intestinal mucosal biology and immunology and SARS-CoV2. He is director of the Center for Celiac Research and Treatment at MGH and widely sought after as an expert in celiac disease, intestinal permeability and autoimmune disorders. Dr. Fasano is the author of Gluten Freedom and co-author with Susie Flaherty of Gut Feelings: The Microbiome and Our Health, published in March 2021 by MIT Press.